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PLCγ1-PKCγ signaling-mediated Hsp90α Plasma Membrane Translocation Facilitates Tumor Metastasis

2014/09/01 02:00

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PLCγ1-PKCγ signaling mediates the membrane translocation of Hsp90α to facilitate tumor metastasis.

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The regulatory mechanism of a client kinase controlling its own release from Hsp90 chaperone machinery through phosphorylation